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Effect of Oral Calcium Supplementation on Lipid Profile and Atherogenic Index of Plasma

Author

Tint Swe Latt,

Related Institution

Publication Information

Publication Type
Journal
Publication Sub Type
Journal Article, Original
Title
Journal of the ASEAN Federation of Endocrine Societies
Frequency
Semi-Annual
Publication Date
November 2014
Volume
29
Issue
2
Page(s)
135-140

Abstract

Methodology. This study was undertaken in 28 centrally obese male subjects [age 26.4 (6.5) years], BMI 31.6 (4.7) kg/m2, WC 99.4 (6.4) cm. All participants received six tablets of CaCO3  (250 mg of elemental calcium/ capsule, for a total of 1500 md/day) for 8 weeks. Serum lipid profile including triglyceride, total cholesterol, HDL-C, LDL- C was measured at baseline and after intervention. AIP was calculated by using formula = log (TG/HDL-C). 


Results. Oral calcium supplementation achieved a 22% (36 mg/dL, p<0.001) reduction in Triglyceride  from baseline [163.4 (37.9) mg/dL] and 19.2% ( 5.8 mg/dL, p<0.001) increase in HDL-C from baseline [30.4 (7.4) mg/dL)]. There were no significant treatment effects on total cholesterol [217.1 (41.21) mg/dL vs 196.3 (46.2) mg/dL] and LDL-C [155.4 (45.1) mg/dL vs 136.3 (45.1) mg/dL]. Significant reduction in serum total cholesterol and LDL-C level was only found in dyslipidemic centrally obese subjects. AIP decreased significantly by 51% with calcium carbonate treatment [median and interquartile range; 0.35 (0.29-0.44) vs 0.17 (0.04-0.44), p<0.01]. 


Conclusion. Eight-week calcium supplementation at 1500 mg/day led to a significant change in lipid levels and AIP. 


 

To assess the effect of oral calcium supplementation on lipid profile and atherogenic index of plasma (AIP).


 

Objectives

To assess the effect of oral calcium supplementation on lipid profile and atherogenic index of plasma (AIP).


 

References

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